| Family |
Member |
Species |
| Adenosine | A1 A2A A2B A3 | human |
| Adenosine | A1 A2B | mouse |
| Adenosine | A2A | rat |
| Adrenergic | alpha 1A alpha 1B alpha 2A alpha 2B alpha 2C beta 1 beta 2 beta 3 | human |
| Adrenergic | beta 2 beta 3 | mouse |
| Adrenergic | beta 2 | rat |
| Anaphylatoxin | C3AR1 C5R1 GPR77 | human |
| Anaphylatoxin | C3AR1 C5R1 GPR77 | mouse |
| Anaphylatoxin | C5R1 | rat |
| Angiotensin | AT1 AT2 | human |
| Angiotensin | AT1 | rat |
| Apelin | APJ | human |
| Apelin | APJ | mouse |
| Apelin | APJ | rat |
| Bile Acid | GPBA | human |
| Bile Acid | GPBA | mouse |
| Bile Acid | GPBA | rat |
| Bombesin | BB1 BB2 BB3 | human |
| Bombesin | BB2 | mouse |
| Bombesin | BB1 | rat |
| Bradykinin | B1 B2 | human |
| Bradykinin | B1 | mouse |
| Calcitonin | CALCRL CT | human |
| Calcitonin | CT | mouse |
| Calcium-Sensing Receptor | CASR | human |
| Calcium-Sensing Receptor | CASR | rat |
| Cannabinoid | CB1 CB2 GPR55 | human |
| Cannabinoid | CB1 CB2 GPR55 | mouse |
| Chemokine | CCBP1 CCBP2 CCR1 CCR10 CCR2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCRL1 CCRL2 CMKLR1 CX3CR1 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7/CMKOR1 XCR1 | human |
| Chemokine | CCBP1 CCBP2 CCR1 CCR3 CCR4 CCR5 CCR6 CCR8 CCR9 CXCR3 CXCR4 CXCR6 CXCR7/CMKOR1 | mouse |
| Chemokine | CCBP2 CCR1 CCR5 CCR6 CCR7 CCR9 CXCR3 CXCR4 | rat |
| Cholecystokinin | CCK1 CCK2 | human |
| Cholecystokinin | CCK1 CCK2 | mouse |
| Citric Acid Cycle Intermediates | GPR91 GPR99 | human |
| Corticotropin-Releasing Factor | CRF1 CRF2 | human |
| Dopamine | D1 D2 D3 D4 D5 | human |
| Dopamine | D2 | mouse |
| Endothelin | ETA ETB | human |
| Endothelin | ETA ETB | mouse |
| Estradiol | GPR30 | human |
| Free Fatty Acid | GPR119 GPR120 GPR40 GPR41 GPR43 GPR84 | human |
| Free Fatty Acid | GPR119 GPR120 GPR40 GPR41 GPR84 | mouse |
| Free Fatty Acid | GPR120 GPR40 | rat |
| Frizzled | FZD1 FZD10 FZD2 FZD4 FZD6 FZD7 FZD9 | human |
| Frizzled | FZD1 FZD10 FZD2 FZD5 FZD6 FZD7 | mouse |
| Gaba | GABA B1 GABA B2 | human |
| Gaba | GABA B1 | mouse |
| Galanin | GAL1 GAL2 GAL3 | human |
| Galanin | GAL2 | mouse |
| Ghrelin | ghrelin | human |
| Ghrelin | ghrelin | mouse |
| Glucagon | GHRH GIP GLP-1 GLP-2 glucagon secretin | human |
| Glucagon | glucagon secretin | mouse |
| Glucagon | secretin | rat |
| Glycoprotein hormone | FSH TSH | human |
| Glycoprotein hormone | TSH | mouse |
| Glycoprotein hormone | TSH | rat |
| Gonadotrophin-releasing hormone | GnRH | human |
| GPRC5 | GPRC5D RAIG1 RAIG2 | human |
| GPRC5 | RAIG1 RAIG2 RAIG3 | mouse |
| GPRC5 | RAIG1 | rat |
| Histamine | H1 H2 H3 H4 | human |
| Histamine | H4 | mouse |
| KiSS1-derived peptide | KiSS1 | human |
| KiSS1-derived peptide | KiSS1 | rat |
| Leukotriene/Lipoxin | ALX BLT1 BLT2 CysLT1 CysLT2 OXE | human |
| Leukotriene/Lipoxin | CysLT1 CysLT2 | mouse |
| Lysophospholipid | LPA1 LPA2 LPA3 LPA4 LPA5 P2Y5 S1P1 S1P3 S1P4 S1P5 | human |
| Lysophospholipid | P2Y5 S1P1 S1P4 S1P5 | mouse |
| Lysophospholipid | LPA1 P2Y5 S1P1 | rat |
| Melanin-Concentrating Hormone | MCH1 MCH2 | human |
| Melanin-Concentrating Hormone | MCH1 | rat |
| Melanocortin | MC1 MC2 MC3 MC4 MC5 | human |
| Melanocortin | MC1 MC3 MC4 MC5 | mouse |
| Melatonin | MT1 MT2 | human |
| Melatonin | MT1 MT2 | mouse |
| Melatonin | MT2 | rat |
| Metabotropic Glutamate | mGlu1 mGlu2 mGlu3 mGlu4 mGlu5 mGlu6 mGlu7 mGlu8 | human |
| Metabotropic glutamate | mGlu3 mGlu8 | mouse |
| Metabotropic Glutamate | mGlu4 | rat |
| Motilin | motilin | human |
| Muscarinic | M1 M2 M3 M4 M5 | human |
| Muscarinic | M1 M5 | mouse |
| N-formylpeptide | FPR1 FPRL2 | human |
| Neuromedin U | NMU1 NMU2 | human |
| Neuromedin U | NMU1 | mouse |
| Neuropeptide FF/AF | NPFF1 NPFF2 | human |
| Neuropeptide head activator | GPR37 | human |
| Neuropeptide S | NPS NPS (2) NPS Ile107 | human |
| Neuropeptide S | NPS | mouse |
| Neuropeptide W/B | NPBW1 NPBW2 | human |
| Neuropeptide W/B | NPBW1 | rat |
| Neuropeptide Y | Y1 Y2 Y4 Y5 | human |
| Neuropeptide Y | Y1 Y2 Y5 | mouse |
| Neurotensin | NTS1 NTS2 | human |
| Nicotinic Acid | GPR109A/HM74A GPR109B GPR81 | human |
| Nicotinic Acid | GPR109A/HM74A | mouse |
| Opioid | delta kappa mu NOP | human |
| Opioid | kappa mu NOP | mouse |
| Opioid | delta kappa mu NOP | rat |
| Opsin-like | OPN1SW | human |
| Opsin-like | OPN4 | mouse |
| Orexin | OX1 OX2 | human |
| Orphan | ADMR CD97 EBI2 EMR1 ETLD1 GPR1 GPR101 GPR107 GPR110 GPR114 GPR116 GPR12 GPR123 GPR128 GPR133 GPR135 GPR139 GPR143/OA1 GPR146 GPR148 GPR15 GPR151 GPR153 GPR155 GPR160 GPR161 GPR171 GPR172A GPR173 GPR174 GPR175 GPR176 GPR18 GPR19 GPR21 GPR22 GPR25 GPR26 GPR3 GPR31 GPR32 GPR34 GPR35 GPR37L1 GPR45 GPR48 GPR52 GPR56 GPR6 GPR61 GPR62 GPR63 GPR64 GPR75 GPR78 GPR82 GPR83 GPR85 GPR87 GPR88 GPR89 GPR97 GRCA/GPR162 MAS1 MAS1L MRGD MRGE MRGF MRGX1 MRGX2 MRGX3 MRGX4 OPN3 P2RY10 P2RY8 PSGR RAIG3 TM7SF1 | human |
| Orphan | ETLD1 GPR1 GPR114 GPR12 GPR128 GPR141 GPR143/OA1 GPR146 GPR15 GPR153 GPR156 GPR157 GPR160 GPR17 GPR171 GPR173 GPR175 GPR176 GPR18 GPR20 GPR21 GPR22 GPR26 GPR35 GPR37 GPR45 GPR56 GPR61 GPR64 GPR75 GPR80/GPR99 GPR82 GPR85 GPR87 GPR97 GRCA/GPR162 MAS1 MRGF OPN5/GPR136 RGR RHO | mouse |
| Orphan | GPR157 GPR160 GPR18 GPR37 GPR85 MAS1 | rat |
| Parathyroid Hormone | PTH1 PTH2 | human |
| Parathyroid hormone | PTH1 | mouse |
| Platelet-activating factor | PAF | human |
| Prokineticin | PK1 PK2 | human |
| Prokineticin | PK1 PK2 | mouse |
| Prolactin-releasing peptide | PrRP | human |
| Prolactin-releasing peptide | PrRP | mouse |
| Prostanoid | DP1 DP2/GPR44 EP1 EP2 EP3 EP4 FP IP1 TP | human |
| Prostanoid | DP1 EP2 EP3 EP4 FP IP1 | mouse |
| Protease-activated | PAR1 PAR2 PAR3 PAR4 | human |
| Protease-activated | PAR1 PAR2 | mouse |
| Protease-activated | PAR1 PAR2 | rat |
| Purinergic | P2Y1 P2Y11 P2Y12 P2Y13 P2Y14 P2Y2 P2Y4 P2Y6 | human |
| Purinergic | P2Y10 P2Y12 P2Y13 P2Y14 P2Y2 P2Y4 P2Y6 | mouse |
| Purinergic | P2Y12 P2Y14 P2Y6 | rat |
| Relaxin | RXFP1 RXFP3 RXFP4 | human |
| Relaxin | RXFP3 RXFP4 | mouse |
| Serotonin | 5-HT1A 5-HT1B 5-HT1D 5-HT1E 5-HT2A 5-HT2B 5-HT2C 5-HT4 5-HT5A 5-HT6 5-HT7 | human |
| Serotonin | 5-HT1D 5-HT1F 5-HT2A 5-HT2B 5-HT5A 5-HT6 5-HT7 | mouse |
| Smoothened | SMO | human |
| Smoothened | SMO | mouse |
| Somatostatin | sst1 sst2 sst3 sst4 sst5 | human |
| SPC/LPC | GPR132 GPR4 GPR65 GPR68 | human |
| SPC/LPC | GPR132 GPR4 GPR65 GPR68 | mouse |
| SPC/LPC | GPR4 | rat |
| Succinate | GPR91 | mouse |
| Tachykinin | NK1 NK2 NK3 | human |
| Tachykinin | NK1 | mouse |
| Thyrotropin-releasing hormone | TRH | human |
| Thyrotropin-releasing hormone | TRH | mouse |
| Trace amine | PNR TA1 TA3 TA4 TA5 | human |
| Trace amine | TA1 TA2 | mouse |
| Trace amine | TA1 | rat |
| Urotensin | UT | human |
| Urotensin | UT | rat |
| Vasoactive Intestinal Peptide | VPAC1 VPAC2 | human |
| Vasoactive intestinal peptide | VPAC1 | rat |
| Vasopressin/Oxytocin | OT PAC1 V1A V1B/AVPR1B V2 | human |
| Vasopressin/Oxytocin | V1A V2 | mouse |
| Vasopressin/Oxytocin | V1A | rat |
| Zinc | GPR39 | human |
