Multispan Inc.

In addition to stable cell lines expressing variety of GPCRs, we are proud to introduce cell lines expressing high quantities of GPCRs on the surface. These cell lines express up to 2x10⁶ molecules per cell that are fully functional as evidenced by normal Ca++ influx. These cell lines thus present a unique source of high quality GPCR proteins for variety of applications, including:
• Antibody generation using antigens with natural epitopes at high expression level
• Cell-based or membrane receptor binding assays to achieve high signal-to-noise ratio
• Cell-based functional assays for hard-to-express GPCRs
• Structural studies as high quality source of protein for crystallization